The book's title refers to Behe's scorn for biologists' failure to appreciate the complexity of the unit of life: the living cell or 'Darwin's Black Box'. He accuses too many biologists of ignorance of protein chemistry and regards their view of the cell's chemical complexity as no more than a mysterious 'Black.

Behe writes a controversial 300-page book that takes a challenging view of the current state of the failure of biological orthodoxy to provide detailed biochemical explanations for several of the vital processes in living cells. This review checks Huxley's predictions the essay concludes with the reviewer's comparable predictions for 2032. Huxley was keenly aware of the distinction between science and technology and it is the misuse of new scientific knowledge in the form of dangerous technology that he was alerting us, especially in the hands of an all-powerful technocratic state that knew how to manipulate its citizens through psychology rather than brute terror, as Orwell portrayed in the other famous dystopian novel, 1984. The essay component here views this novel as an allegory of today's world being panicked into a radical 'Restart' into a promised utopia by the New World Order. The story is set in a future fictitious One World State, whose citizens are environmentally engineered into an intelligence-based social hierarchy based on advanced technology in reproduction, sleep-learning with psychological manipulation through classical conditioning.

This was Huxley's fifth novel but his first dystopian science fiction attempt.

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